- ABC is new with Extreme Makeover: Home Edition, Desperate Housewives and Brothers & Sisters
- CBS is new with The Amazing Race 10, Cold Case and Without a Trace
- The CW is new with Everybody Hates Chris, All of Us, Girlfriends and The Game
- Showtime has Dexter
- HBO has The Wire
- E! is new with THS Investigates Starving for Perfection, The Girls Next Door and House of Carters
- VH1 is new with The Flavor of Love