- ABC is new with Extreme Makeover: Home Edition, Desperate Housewives and Brothers & Sisters
- CBS is new with The Amazing Race 10, Cold Case and Without a Trace
- FOX is new with The Simpsons, American Dad, Family Guy and The War at Home
- The CW is new with 7th Heaven
- HBO has The Wire and Russell Simmons' Def Comedy Jam
- Showtime has Dexter
- VH1 is new with Hogan Knows Best, Breaking Bonaduce and Celebrity Paranormal Project