Reese Witherspoon shows off her serious side (can't you tell from the photos?!) in the February issue of Marie Claire, putting away her trademark smile to talk about her charity work. Awww, cheer up, Reese! Over the Summer, Reese was named the first-ever Avon Global Ambassador, which is a topic near and dear to her heart these days and something she wants to talk about, but she also got in some nice words about her new co-star Vince, too. Here's more:

  • On taking on the role of Avon Ambassador: The Avon Foundation has been hugely active in the fight against breast cancer — and also in the areas of domestic violence and disaster relief. I went to New Orleans in the wake of Hurricane Katrina, and it was devastating to see how underserved those communities are. I'm looking forward to helping raise money and awareness for those causes. In fact, over the years, I've been approached by many companies to support their brands or products, but I've never felt as inspired as when I met the people from Avon — I feel like they've given me an opportunity to connect to women in a very personal way.
  • On Vince: "I’ve been a big fan of his for so many years. Vince is one of the only actors working today who makes me laugh in every movie I see him in. Working with him has been a great experience for me, a real exercise in always staying on my toes comedically. I laugh every day at work!"

That makes both her and Vince who are super complimentary of each other, but I wonder if these interviews were conducted before the rumors of on-set trouble. In the interview she also talks about her upcoming movie Penelope, which looks totally weird, don't you think?