- ABC is new with Wife Swap, The Bachelor: Rome and the premiere of What About Brian
- NBC is new with Deal or No Deal, Heroes and Studio 60 on the Sunset Strip
- CBS is new with The Class, How I Met Your Mother, Two and a Half Men, The New Adventures of Old Christine and CSI: Miami
- The CW is new with 7th Heaven and Runaway
- Showtime is new with Weeds
- MTV is new with Made
- E! is new with Dr. 90210
- Late night highlights include Fergie on The Tonight Show With Jay Leno on NBC and Dane Cook on Jimmy Kimmel Live on ABC
