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Reese Witherspoon Cameo on After Lately (Video)

Video: Reese Witherspoon Pokes Fun at Herself With Chelsea Handler

Reese Witherspoon is returning to Chelsea Handler's show After Lately! After turning in a hilarious performance on the show last year, Reese is back for more in this weekend's episode. We're taking a peek at her cameo — and her real-life friendship with Chelsea — in PopSugar Rush.

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Hi there, I'm Lauren Bradshaw. Reese Witherspoon is returning to Chelsea Handler's show After Lately, and we're taking a look at the women's fun friendship in today's PopSugar Rush. REESE WITHERSPOON: I made you a little something to say thank you for all of your hard work. I'll be right back, it's right upstairs. CHELSEA HANDLER: Oh my god, she is driving me crazy. You guys were right the last time, she is so awful! Reese Witherspoon's awful? The A-list actress is making her second cameo on Chelsea Handler's show After Lately this weekend, and clearly, she's enjoying having a little fun with her image. Remember when she acted like this on the series last March? REESE WITHERSPOON: "You guys are a bunch of narcissistic jerks. It's like Chelsea is running an animal shelter around here, except she's not rescuing a bunch of cats and dogs, she's rescuing failures." It's all in fun, of course. Reese and Chelsea are friends after working on the film This Means War together, and they've been spotted hanging out off-set in their spare time. Chelsea even presented Reese with the Generation Award at the MTV Movie Awards last year. CHELSEA HANDLER: "Reese, it seems like you do everything perfectly. You're smart, you're funny, and after two children, you still have a smaller ass than Justin Bieber . . ." Reese and Chelsea's film This Means War comes to theaters on Valentine's Day, but to see how it all goes down with Reese on After Lately, check out the show this Sunday, January 22 at 11pm.

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