- FOX is new with Prison Break and a repeat of House
- ABC is new with Wife Swap, The Bachelor: Rome and What About Brian
- NBC is new with Deal or No Deal, Heroes and Studio 60 on the Sunset Strip
- CBS is new with How I Met Your Mother, The Class, Two and a Half Men, The New Adventures of Old Christine and CSI: Miami
- The CW is new with Everybody Hates Chris, All of Us, Girlfriends and The Game
- Late night highlights include Sharon Stone on The Tonight Show With Jay Leno on NBC and Pamela Anderson on Jimmy Kimmel Live on ABC
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