- ABC is new with Ugly Betty, Grey's Anatomy and Barbara Walters Special: 30 Mistakes in 30 Years
- FOX is new with 'Til Death then a repeat 'Til Death and then is new with The O.C.
- NBC is new with My Name is Earl, The Office, 30 Rock and ER
- CBS is new with Survivor: Cook Islands, CSI: Crime Scene Investigation and Shark
- The CW is new with Smallville and Supernatural
- MTV is new with Real World/Road Rules Challenge and Rob & Big
- Showtime is new with The Underground
- Late night highlights include Emilio Estevez on The Tonight Show With Jay Leno on NBC