- The CW is new with Gilmore Girls and Veronica Mars
- ABC is new with the premiere of Big Day, Help Me Help You and Boston Legal
- FOX is new with Standoff and House
- FX is new with Nip/Tuck
- CBS is new with NCIS, The Unit and 3 Lbs.
- NBC is new with Friday Night Lights, Law & Order: Criminal Intent and Law & Order: Special Victims Unit
- Late night highlights include George Clooney on Late Show With David Letterman on CBS, Jude Law on Late Night With Conan O'Brien on NBC, Wilmer Valderrama and Chris Daughtry performs on Jimmy Kimmel Live on ABC