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Oprah Winfrey

Oprah Winfrey's big year has been all about her work. She has landed several high-profile and highly coveted interviews on her Orpah's Next Chapter series over the past year, including a one-on-one with Lance Armstrong in January where he talked about his fall from grace for using performance-enhancing drugs while racing. Oprah also got an exclusive chat with Beyoncé Knowles ahead of the release of Beyoncé's HBO film, Life Is But a Dream. Oprah will return to the big screen this August when she stars alongside Forest Whitaker in The Butler.

Oprah Winfrey ranked 9th in the Game Changers category.

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