Is There a TV Costar Curse? 32 Couples That Couldn't Make It Work

Katie Holmes and Joshua Jackson shared a brief relationship while filming the first season of Dawson's Creek in 1998. Katie has since called Josh "her first love."

Jennifer's first husband was actor Scott Foley — the two met when Jen played Scott's out-of-town girlfriend on Felicity back in 1998, and they tied the knot for real in 2000. They stayed together for two-and-a-half years before divorcing, and Jennifer went on to date her Alias costar Michael Vartan. We all know what happened after that.

The O.C. fans rejoiced when the show's most endearing couple, Seth Cohen and Summer Roberts, got together off screen in 2003. Adam Brody and Rachel Bilson were a truly adorable pair, and some of us still haven't recovered from their 2006 breakup. Rachel went on to date Hayden Christensen, while Adam found love with another TV darling, Leighton Meester.

Before tying the knot with Ryan Reynolds in 2012, Blake Lively was coupled up with her Gossip Girl costar Penn Badgley. The two played onscreen lovers Serena and Dan during the show's six-year run but ended their real-life romance in 2010.

Heroes costars Milo Ventimiglia and Hayden Panettiere began dating after meeting on the set in 2006. At the time, Hayden was over 10 years younger than Milo, and they reportedly split over "lifestyle conflicts" in 2009.

Chad Michael Murray and Sophia Bush met on the set of One Tree Hill in 2003 and tied the knot in 2005 after dating for two years. Unfortunately, just like in their onscreen relationship, the couple called it quits — they annulled their marriage and separated just five months later.

Dominic Monaghan and Evangeline Lilly pretty much met in paradise — they began dating in 2004 while filming Lost on set in Hawaii — but ended things five years later.

Emily VanCamp and Dave Annable struck up a relationship in 2007 after playing siblings on ABC's Brothers and Sisters (their chemistry was so strong that producers twisted the show's plot so that they were no longer related). They lasted a little over a year before Emily left the show and Dave's now-wife, Odette Yustman, was cast as his new love interest.

Before she married Cash Warren, gave birth to her three kids, and founded The Honest Company, Jessica Alba starred on Fox's Dark Angel. It was there that she met and began dating her costar Michael Weatherly. The two were engaged in 2001 but ended their relationship in 2003.

Gossip Girl costars Leighton Meester and Sebastian Stan dated for two years before calling it quits in 2010. Of the relationship, Leighton told Seventeen magazine, "I was really sad when it ended." Leighton is now married to Adam Brody, while Sebastian has been linked to Dianna Agron and Jennifer Morrison.

Nina Dobrev and Ian Somerhalder split in May 2013 after more than three years of dating. The couple met while playing star-crossed lovers Elena and Damon on The Vampire Diaries but have managed to remain friends since their breakup, and even after Ian's 2015 wedding to Nikki Reed.

Jason Segel and Linda Cardellini met on the short-lived series Freaks and Geeks and dated for a few years after the show abruptly ended in 2000. Rumor has it that Linda is the one who inspired Jason's infamous nude breakup scene in Forgetting Sarah Marshall.

After her split from Scott Foley, Jennifer Garner began dating her Alias costar Michael Vartan. The pair was a couple both on and off screen before splitting in 2004. Fun fact: Michael went on to play Jennifer Lopez's fiancé in 2005's Monster-in-Law, just a year after Lopez ended her real-life engagement to Ben Affleck, who married Jennifer Garner that same year. Freaky!

Emily VanCamp and Chris Pratt played siblings while starring on Everwood back in 2004 and were a real-life couple until their split two years later.

They may have been known as foster siblings on Dexter, but off screen, Jennifer Carpenter and Michael C. Hall were connected in a different way. The couple divorced in 2011 after three years of marriage but remain close friends and colleagues — both actors have spoken positively about each other in interviews and continued working together through the show's final season.

Jennifer Love Hewitt and Jamie Kennedy met on the set of Ghost Whisperer and dated for a year before calling it quits in 2010.

There was definitely something in that Gossip Girl water — Jessica Szohr and Ed Westwick were one of three real-life couples to come out of the CW show. The pair dated on and off for four years before splitting in 2012.

Jennifer Morrison and Jesse Spencer met in 2004 while shooting the pilot for House. They played a couple on screen but kept their real-life relationship a secret from their fellow costars before getting engaged in 2006. Unfortunately, they never made it to the altar: the couple called off their engagement a year later and officially split in 2007.

After Jamie-Lynn Sigler's guest-starring role as a love interest of Jerry Ferrara's character Turtle on Entourage in 2008, the two began a real-life relationship. They kept their love under wraps for the most part but called it quits a year later. Jamie-Lynn went on to find love with baseball player Cutter Dykstra, whom she has two sons with.

Another TV couple that played brother and sister — Katherine Heigl and Jason Behr portrayed siblings on Roswell and began dating in 1999. The couple was rumored to be engaged, though their love fizzled and they called it quits in 2001. Katherine is now married to musician Josh Kelley.

Back in her Felicity days, girl-next-door Keri Russell dated her onscreen boyfriend Scott Speedman. The two dated from 2000 to 2001 and still remain close friends.

Did you know that Emily VanCamp dated Klaus? Emily met The Vampire Diaries star Joseph Morgan while the two were filming the TV miniseries Ben Hur in 2010, and they remained a couple until splitting in 2011. Emily told Canada's Flare magazine that distance was the reason for their breakup, saying, "I'm working nonstop in LA; he's working in Atlanta. It kind of makes it impossible."

Before hooking up with Nina Dobrev, Ian Somerhalder dated his Lost costar Maggie Grace. The two quietly dated after getting killed off the hit show in 2006 but ended their relationship the following year.

Brian Austin Green may be married to Megan Fox now, but back in the late 1990s, he dated his Beverly Hills, 90210 costar Vanessa Marcil. The two welcomed a son, Kassius Lijah, in 2002.

Milo Ventimiglia and Alexis Bledel dated for four years between 2002 and 2006 as they starred (and played a couple) on Gilmore Girls. Milo went on to date his Heroes costar Hayden Panettiere, while Alexis found love with her Mad Men castmate Vincent Kartheiser — the two married in August 2014.

Vanessa Hudgens and Zac Efron were definitely a Disney golden couple. The two met while filming the first High School Musical television movie in 2005 and dated until December 2010, after starring in all three installments together.

One Tree Hill stars certainly had the hots for each other! After her divorce from costar Chad Michael Murray in 2006, Sophia Bush cozied up to another castmate, Austin Nichols — and the two remained a couple on and off for six years. They called it quits in February 2012.

Even though Kaley Cuoco and Johnny Galecki played lovers on The Big Bang Theory, nobody knew that they were linked up in real life, too! The pair dated secretly for almost two years and didn't reveal that they were a couple until calling it quits in 2010. Secret lovers, indeed.

The Glee costars got engaged in July 2013 and secretly married in 2015. They announced their plans to divorce in January 2017, citing irreconcilable differences.

The couple met on the set of Killer Movie in 2007 and struck up a romance. They were married in a private ceremony in April 2011, and Torrey joined the cast of Paul's show, The Vampire Diaries, that same year. They filed for divorce just two years later.

Chad and Kenzie, who was seven years his junior, met in 2006 while working together on One Tree Hill. They got engaged that same year — when Dalton was a senior in high school. After a seven-year engagement, the two called it quits.

The pair first met on the set of Riverdale back in 2017, and after playing fan-favorite couple Jughead and Betty on screen, they eventually took their relationship off screen. After almost two years of dating, their split was announced in July 2019.