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58. Lady Gaga

Lady Gaga had an over-the-top 12 months complete with wacky outfits and elaborate performances. It seemed like everyone wanted a piece of Gaga — she teamed up with Elton John at the Grammys and later collaborated with Beyonce Knowles on their song and video for "Telephone." She was rewarded for her innovative work by earning a place on Time's list of the Most Influential People.

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