After the initial "aw, man!" I'm coming around to the news a little, as I trust HBO to do something cool and Rita Wilson would apparently be an executive producer on the project. The series would follow "the life of Calliope Stephanides and the epic family history that may hold the answer to her complicated sexual identity."
Like Revolutionary Road, which I read long before there was news of a movie, the writing in Middlesex is so rich and evocative, I can't imagine how a screen adaptation could possibly do it justice. Then again, I'm relieved that it'll be a TV series and not a movie, so hopefully they can take their time with this story and avoid trying to cram everything in (while also sacrificing crucial elements) from the book.
Have you read Middlesex? Have you ever seen book-to-screen adaptation news that got a rise out of you?