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But I'm a Cheerleader

Lyonne really broke out in the 1999 cult classic But I'm a Cheerleader, another project with a strong LGBT point of view. Rent it if you can, and if you can't but still want to see her, she also turns up in Kristen Wiig's Girl Most Likely. She has a few upcoming films, including Kevin Smith's horror-comedy, Yoga Hosers.

Image Source: Lionsgate