As of late, I've taken a strong liking to the combination of leather and wool, or leather and knit. I think Molly Sims's Elizabeth and James skirt sparked it. Leather on its own can be intense, but the addition of another fabric softens it up. If I could, I'd get this Helmut Lang Leather and Wool Dress ($875). It's modern and futuristic at the same time, but it's way too pricey for me.
See the look for less.
Urban Renewal has come out with this Leather and Knit Bodycon Dress ($68) that has the same motif as the Helmut Lang version. Yes, the silhouette is a tad different, but you get the gist. I especially dig the sweetheart neckline because it makes the dress appear more womanly. Now I can get my leather/knit fill without spending a ton.