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Pregnancy Quad Screenings

Lil Community: Advice For a Positive Quad Screening

This question was submitted by amberetta1 in the Pregnancy Posse group.

I just got a call from my OBGYN this morning that my quad screen results showed an increased AFP, making me "at risk" for neural tube defect. I have been Googling and searching all morning. I realize that this could mean absolutely nothing, and I'm trying not to freak out. I have a sonogram scheduled in two weeks for "a detailed ultrasound of baby's anatomy". I am 17 weeks.

Has anyone else had this happen and what was your outcome?

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amberetta1 amberetta1 6 years
Thanks ladies for the support ;) I'm also surprised to see this as a "featured topic". I am trying to just relax and go with the flow; the things I HAVE read all say basically the same thing, ex: out of 1000women tested, 50 will test positive for increased risk, and out of those 50, only maybe 2 will truly have a defect. I think it just really shocked me b/c I kinda just went and did the test, ladi-da, not really thinking anything would come out of it. So when I got that phone call...well it just really hit me. Thanks again for the support and advice, and I will definitely keep you posted on the outcome of my US next week. =)
runningesq runningesq 6 years
I can't offer you any other advice than STEP AWAY FROM GOOGLE ! There is a lot of information on the internet, and most of it is pure junk. Hang in there ((()))
flyinggrip flyinggrip 6 years
If only the AFP was high, then your risk is probably only elevated for a neural tube defect, like spina bifida. If the other markers on the test are higher or lower than average, then the risk for other disorders like Down syndrome or Trisomy 13 or 18 might be elevated. Its important to remember that this is just a screening test and does not mean that there is something wrong with your baby. Your doctor will probably suggest a more detailed level II ultrasound to look more closely at the baby's spine and other organs. Another option, is to pursue AFP testing via amniocentesis. This will tell how much AFP is in the amniotic fluid which can be more informative that the amount that is in your blood and this test can also look at the baby's chromosomes if there is an increased risk for DS or Tri 13/18. Try not to worry too much and don't read too much online, a lot of what you find is the worst case scenarios. Speak with your doctor or genetic counselor instead.
LilaBo LilaBo 6 years
got a false positive result with BOTH my girls, and totally freaked out the first time. they are both healthy, happy and feisty as ever! :)
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