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Afleet Alex (2005)

After coming in third in the Derby, Afleet Alex overcame a serious stumble in the Preakness to win by 4 3/4 lengths. A few weeks later, he took the Belmont. Afleet Alex's owners donated a portion of his winnings to Alex's Lemonade Stand, a charity founded by young cancer patient Alexandra Scott to benefit pediatric cancer research.

Image Source: Getty