In Dallas Buyers Club, Jared Leto plays Rayon, a HIV-positive transsexual who teams up with Matthew McConaughey's cowboy hustler — who also has AIDS — to bring unapproved drugs to other desperate victims of the virus. He was so committed to the role that he only really met his costars for the first time as himself very recently. So what was their first non-Rayon interaction like? And what is his least favorite thing about wearing women's clothing? We got the scoop at the Mill Valley Film Festival from Jared himself.