In 2006's Talladega Nights: The Ballad of Ricky Bobby, Ferrell's and Reilly's characters go from best friends to nemeses, but two years later, it's the opposite in Step Brothers. We watch their characters become best friends before our eyes, and in real life, it appears the two are tight, having been spotted hanging out at basketball games (they once jokingly kissed on the Kiss Cam!).
Will Ferrell and John C. Reilly
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