If you have a baby or small child, be sure to quickly give the room a once-over. You'd be surprised at the things that are left under a bed (that you'd never want your child to play with). Also, when my kids were babes, I always traveled with a baby-proofing kit (a few outlet covers, table-corner covers, tape, rubber bands, etc.) so that I could take care of the obvious dangers.
Source: Flickr user Joe Shlabotnik