A new trailer for Disney's upcoming A Wrinkle in Time adaptation [1] is here! The action-packed and star-studded trailer includes appearances by Oprah Winfrey [2] as Mrs. Which, Chris Pine [3] as Dr. Alexander "Alex" Murry, Reese Witherspoon [4] as Mrs. Whatsit, and Mindy Kaling as Mrs. Who. Watch the first trailer above to see how director Ava DuVernay [5] brings to life Madeleine L'Engle's 1963 novel, as well as the latest trailer below. A Wrinkle in Time hits theaters on April 6, 2018.