The vice presidential debate aired from Virginia on Tuesday night. Mike Pence and Tim Kaine sparred for 90 minutes over several issues [1] ranging from ISIS to abortion. Twitter shared the night's most talked-about moments [2] — here are the top three.

3. When Kaine and Pence argued over Russia and Vladimir Putin's aggression.

Tim Kaine: "You guys love Russia." #VPDebate [3] pic.twitter.com/0Z1NByrVDX [4]

— USA TODAY (@USATODAY) October 5, 2016 [5]

2. When Kaine and Pence discussed the use of nuclear weapons.

Kaine on nuclear weapons: Trump could be the "fool or maniac" who triggers a "catastrophic event" #VPDebate [6] https://t.co/M0k6U1PZgk [7]

— CNN Politics (@CNNPolitics) October 5, 2016 [8]

1. When Pence responded to Kaine's remarks about Trump calling immigrants rapists with "that Mexican thing."

.@Mike_Pence [9]: "You whipped out that Mexican thing again."@TimKaine [10]: "Can you defend it?" #VPDebate [11] #debatenight [12] #debates [13] #Debates2016 [14] pic.twitter.com/UCJJpFuIdf [15]

— CSPAN (@cspan) October 5, 2016 [16]