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Jennifer Aniston

In 1989, Jennifer Aniston wasn't an A-lister, but rather an unknown actress promoting Nutrisystem on The Howard Stern Show. The shock jock spent part of her appearance speculating about her breast size. Despite being cast in a few shows, none of them took off, and the actress was desperate for her big break. Years later, Warren Littlefield, the former president of entertainment at NBC, shared a conversation he had with Jennifer. "[It's] 10:30 p.m. at night on Sunset Boulevard," he said. "I'm at the Chevron station gassing up, and Jennifer is over at the other island, and she comes over, and she says, 'Is it ever going to happen?' and I say, 'We believe in you. I love you. I so believe in your talent, I'm sure it will.' A few months later, we handed her the Friends script."

Image Source: Getty / NBC