On how she met Our Brand Is Crisis producers George Clooney and Grant Heslov: "Grant, George, and the person I dated were all friends. I met George at a party where he was doing Buddy Hackett imitations! George was the reason the guy that I ended up dating dated me. He was like, 'If you don't get with her, I'm gonna get with her.' He was kidding but sort of pushing. So we've all known each other for umpteen-chillion years and have supported each other from afar."
On her privacy: "I've always been insanely private. When I [first] stepped into this, it was still loud. The tabloids were violating. I went, 'How can people write that?' I spent a year and a half, two years, distraught, saying, 'You can't say these lies.' I spent years fighting battles you can't win. As loud as it's gotten now, it's the same panic. As much as I profess to being able to shut it out, there are times I can't, like when it's hurtful to people I care about. Me, I get it. But when it hurts other people? Like, you come after my son, I'm gonna go postal. But they do."
On her son, Louis, and current issues facing black men and women: "You see how far we've come in civil rights — and where we've gotten back to now. I want my son to be safe. I want my son to be judged for the man he is. We are at a point now where if we don't do something, we will have destroyed what so many amazing people have done. You look at women's rights; it's turning into a mad, mad world out there. But sometimes it needs to get really loud for people to say, 'I can't unsee this.' If I could ride in a bubble with him for the rest of his life, I would. But I can't."