Differin Acne Treatment Gel ($24, originally $37)
"Retinoids not only treat acne but are also shown to have multiple antiaging benefits," Dr. Reddy says, and his over-the-counter choice is the Differin Acne Treatment Gel. The 0.1 percent adapalene treatment helps treat acne and is more tolerable than other prescription retinoids like tretinoin. It's best to use this treatment in your nighttime routine with a sunscreen in the morning. Read more in our Differin Acne Treatment Gel review.
- Pros: FDA-approved retinoid, effective at treating and preventing acne, also helps with fine lines and skin texture
- Cons: Can cause dryness or irritation during the first few weeks of use, requires consistent sunscreen use
- Type: Topical retinoid treatment (adapalene 0.1%)
- Finish: Lightweight gel
- Who it's best for: Acne-prone skin, beginners looking to start a retinoid routine with something gentle but effective
- Extras: Available over the counter and FSA/HSA eligible
Editor Quote: "I gladly buy myself a refill of this Differin Gel every time I'm running low, which happens about every month and a half." – Jessica Harrington, beauty section lead
