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Is There a TV Costar Curse? 32 Couples That Couldn't Make It Work
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Milo Ventimiglia and Hayden Panettiere

Heroes costars Milo Ventimiglia and Hayden Panettiere began dating after meeting on the set in 2006. At the time, Hayden was over 10 years younger than Milo, and they reportedly split over "lifestyle conflicts" in 2009.

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