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Holmes's first wife was journalist Amy Ferson. There isn't all that much known about Ferson or her relationship with Holmes (including when exactly they met and married), but Us Weekly reports they divorced in 2007. They share two children together, Brianna and Jaiden, according to People.
Much like her ex, Ferson appears regularly on news television, only on the political news beat. Check her out reporting on the 2020 presidential election on "The Heat."