The "Friends" Cast and Other Stars React to Matthew Perry's Death: "So Utterly Devastated"

Wheeler, who played Chandler's on-and-off girlfriend Janice in the TV sitcom, took to Instagram to express her sadness on Oct. 29. Alongside a photo of the pair in "Friends," she wrote: "What a loss. The world will miss you Matthew Perry. The joy you brought to so many in your too short lifetime will live on. I feel so very blessed by every creative moment we shared."