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Based on journalist Michael Pollan's book of the same name, this docuseries follows Pollan as he explores different types of psychedelics and the ways they are being used in medicinal contexts across the globe. LSD, psilocybin, MDMA, and mescaline each get their own episodes, which trace each substance's fascinating history, use, criminalization, and potential ability to solve mental health issues from PTSD to depression and beyond.