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21 Celebrities You Forgot Guest Starred on Sister, Sister — Yep, That's Brittany Murphy!
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Rachael Harris Guest Starred on Sister, Sister

Rachael Harris guest starred on Sister, Sister as Simone, a bossy college senior, in the season six episodes "Home Sweet Dorm," "Stop in the Name of Fun," "Home Court Advantage," "We Are Family," and "The Domino Effect."

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