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In 2006, no one was expecting to fall in love with Calle 13. But the duo, formed by brothers René Pérez and Eduardo Cabra, made quite an impression with their approach to reggaetón and their catchy lyrics. At the seventh-annual Latin Grammys, they were nominated for best new artist, best urban music album, and best short-form music video — and they won all three. It was definitely the beginning of an era for one of the most influential artists of this generation.