The reason that someone seeks plastic surgery is personal, complex, and emotional, and this show treats it as such. In each episode, skin and beauty expert Jamie Sherrill (known as Nurse Jamie) and plastic surgeon Sheila Nazarian, MD, see two patients with stories that have led them to seek plastic surgery. One was a domestic abuse and gunshot survivor who wanted to forget the past. Another struggled after having quadruplets and wanted to take back her body. One hoped to complete their transition to finally feel more like themselves. After hearing each patient's story, they are provided with a unique procedure plan that's either performed by Nurse Jamie, through the use of fillers and lasers, or Dr. Nazarian, for surgery.