24 Medical-Grade Skin-Care Finds From Dermstore, Including Major Deals

SkinMedica Age Defense Retinol Complex 1.0 ($96)

Retinol is the gold standard when it comes to antiaging, besides sunscreen. One pump of SkinMedica's Age Defense Retinol Complex 1.0 nightly is all you need to reduce the appearance of fine lines or wrinkles, and diminish dark spots for good. This retinol is formulated in a base of antioxidants, ceramides, peptides, and niacinamide to keep your skin calm while it reaps the retinol benefits.