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Cortisone shots are administered by dermatologists to help heal deep, cystic pimples, reduce swelling, and speed up the recovery process of the zit. Though the risk of getting a cortisone shot around the same time as your COVID-19 vaccine is very small, there's still one thing to consider.
"A potential problem with getting a cortisone shot in a pimple around the time you are getting your COVID-19 vaccine is a decreased immune response, which could reduce vaccine efficacy," Anna Karp, DO, board-certified dermatologist at the Skin Institute of New York Dermatology, told POPSUGAR.
Again, this is a minor risk because only a very small amount of cortisone is typically injected into pimples, but if you want to be extra cautious, Dr. Karp recommended waiting "at least a week before and a week after" getting vaccinated before doing a steroid injection.