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Frequent face washing can also increase skin irritation, again leading to more maskne flare-ups. So, after washing your face, always make sure to follow up with a lightweight moisturizer. "Hyaluronic-acid containing facial moisturizers can help," Dr. Harold Lancer, MD previously told POPSUGAR. "Sometimes a triple antibacterial ointment like Neosporin can be applied, when necessary, to the affected area."