Is There a TV Costar Curse? 32 Couples That Couldn't Make It Work

Emily VanCamp and Dave Annable struck up a relationship in 2007 after playing siblings on ABC's Brothers and Sisters (their chemistry was so strong that producers twisted the show's plot so that they were no longer related). They lasted a little over a year before Emily left the show and Dave's now-wife, Odette Yustman, was cast as his new love interest.