All the Stars We've Lost in 2022

Aycox, best known for playing Meg Masters on "Supernatural," died on Nov. 16 at the age of 47. Her sister, Susan Raab Ceklosky, confirmed the news in a Facebook post. "My beautiful, smart, fierce, incredibly talented, and loving sister-in-law, Nicki Aycox Raab, passed away yesterday with my brother, Matt Raab, by her side," she wrote. "Nicki and Matt had a wonderful life together in California. She was definitely a fighter and everyone who knew her loved her 💔."

A cause of death has not been confirmed, though Aycox had been fighting leukemia at the time of her death, which she often posted about on her Instagram page.