Melissa McCarthy's Funniest Onscreen Moments of All Time

By Quinn Keaney

Updated on Aug 26, 2016 at 4:00 PM

Everett Collection

Everett Collection

Melissa McCarthy has been nothing short of hilarious in movies like Bridesmaids and Spy, as well as her TV work on Mike and Molly and Saturday Night Live, to name a few roles. Thanks to a sense of physical comedy that would make Lucille Ball proud (we're convinced that every time McCarthy throws herself down a flight of stairs, an angel gains its wings) and impeccable comedic timing, she's solidified herself as one of Hollywood's most hysterical leading ladies. Keep reading to see all of her best onscreen moments, and check out her incredible appearance on Lip Sync Battle.

01

When Her Unfortunate Bridesmaids Bowel Movement Puts You Off Chipotle For a Good Month — Universal Pictures

When Her Unfortunate Bridesmaids Bowel Movement Puts You Off Chipotle For a Good Month

God bless you, Megan.

02

When the Only Identity She's Going to Be Thieving Is Kelis's — Universal Pictures

When the Only Identity She's Going to Be Thieving Is Kelis's

03

When Her Bold Flirting Technique Makes Your Tinder Inbox Look Like Child's Play — Universal Pictures

When Her Bold Flirting Technique Makes Your Tinder Inbox Look Like Child's Play

04

When This SNL Quote Gives You Inspiration For a New Twitter Bio — NBC

When This SNL Quote Gives You Inspiration For a New Twitter Bio

05

When You Wish It Was Possible For Her to Be Your Zumba Instructor — Universal Pictures

When You Wish It Was Possible For Her to Be Your Zumba Instructor

06

When She Finally Finds a Use For a Phonebook in 2016 — 20th Century Studios

When She Finally Finds a Use For a Phonebook in 2016

07

When She Rolls Down the Stairs and It's So Funny You Start Doing One of Those Weird, Silent, Heaving Laughs — NBC

When She Rolls Down the Stairs and It's So Funny You Start Doing One of Those Weird, Silent, Heaving Laughs

08

When She Tells Rose Byrne What's Up in Spy — 20th Century Studios

When She Tells Rose Byrne What's Up in Spy

09

When You Realize You'd Rather Face Down the Jigsaw Killer Than Look at Her Terrifyingly Hilarious Face For One More Moment — Everett Collection

When You Realize You'd Rather Face Down the Jigsaw Killer Than Look at Her Terrifyingly Hilarious Face For One More Moment

Sorry, Kristen Bell, but The Boss might be too much to handle.

10

When Tammy Perfectly Encapsulates How You Feel After Drunkenly Eating McDonalds — Warner Bros.

When Tammy Perfectly Encapsulates How You Feel After Drunkenly Eating McDonalds

11

When Her Obsession With Ranch Goes One Step Too Far — NBC

When Her Obsession With Ranch Goes One Step Too Far

12

When She Dances With Sandra Bullock, and All of Your Wildest Comedic Fantasies Come True — 20th Century Studios

When She Dances With Sandra Bullock, and All of Your Wildest Comedic Fantasies Come True

13

When She Says What You're Thinking Every Time You Lay Eyes on Chris Evans — Universal Pictures

When She Says What You're Thinking Every Time You Lay Eyes on Chris Evans

14

When This Frantic Gilmore Girls Moment Makes You Smile For Approximately 6 Minutes Straight — The CW

When This Frantic Gilmore Girls Moment Makes You Smile For Approximately 6 Minutes Straight

15

When She Literally Flips Out on Mike and Molly — CBS

When She Literally Flips Out on Mike and Molly

16

When She Joins Kristen Wiig in Looking Like an Extra From The Hills Have Eyes — NBC

When She Joins Kristen Wiig in Looking Like an Extra From The Hills Have Eyes

17

When Her Couch Flop Brings You Endless Joy — Universal Pictures

When Her Couch Flop Brings You Endless Joy

18

When You Still Love Her Despite Her Choice to Wear Crocs — Warner Bros.

When You Still Love Her Despite Her Choice to Wear Crocs

19

When She Gives You the Perfect, Quotable Bachelorette Party Plan to Offer Your Newly Engaged Friends — Universal Pictures

When She Gives You the Perfect, Quotable Bachelorette Party Plan to Offer Your Newly Engaged Friends

20

When She Falls For the 100th Time, and It Still Kills You — Universal Pictures

When She Falls For the 100th Time, and It Still Kills You

21

When Her Top-Secret Spy Mission Doesn't Go as Planned — 20th Century Studios

When Her Top-Secret Spy Mission Doesn't Go as Planned

22

When She Keeps Things Super Classy — Universal Pictures

When She Keeps Things Super Classy

23

When This Scene in The Heat Makes You Double Over in Laughter — 20th Century Studios

When This Scene in The Heat Makes You Double Over in Laughter

24

When She Is Your Bad Breakup Inspiration — The CW

When She Is Your Bad Breakup Inspiration

25

When She Rocks a Cat Sweater Way Better Than Your Aunt Sue Ever Could — 20th Century Studios

When She Rocks a Cat Sweater Way Better Than Your Aunt Sue Ever Could