Alex (Justin Chambers) and Meredith (Ellen Pompeo) have been friends since the start, and they know each other better than anyone. They've lived together in Meredith's house, and they're always there to support each other through the toughest times — like when Izzie leaves Alex. They're so similar to each other, and that's why they make a great duo — but just as friends.
Meredith and Alex, Grey's Anatomy
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