Every Movie Oprah Has Been in Over the Past 33 Years

Making her return to TV movies, this time for HBO, Winfrey's starring role in the film adaptation of the book The Immortal Life of Henrietta Lacks was tailor-made for her. Not only does the film, which follows a daughter who discovers that her late mother's cells influenced medical advancements for decades, display Winfrey's natural talent for drama acting, but it also gives the actress another opportunity to tell a true story.