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"Grey's Anatomy" debuted a blockbuster two-part episode in February 2006, with "It's the End of the World" playing after the Super Bowl and "As We Know It" debuting a week later. In the episode, a patient comes to the hospital with an unexploded bazooka rocket in his chest. What follows is the most intense operation in Seattle Grace history, with Cristina, Meredith, Burke, and Derek all in on the action and the bomb squad in the OR. Eventually, they get the bazooka rocket out — though two members of the bomb squad die. At the end of the second part, Derek and Meredith share a romantic moment, and even though they're not together at this point, it's clear their love isn't really in the past.