10 Grey's Anatomy Breakups That Destroyed Our Fragile Hearts

The truth is a bitter pill to swallow, especially when John Legend croons "All of Me" in the background. After operating in the dark, Cristina expresses her love for the O.R. to Owen. She then asks him if he had wanted to adopt a patient's son, who would have gone into a foster home if neither of his parents woke up. The hard questions continue. She asks if she will ever be enough for him. Radio silence. The cardiothoracic surgeon leaves, telling Owen she wishes it were different. Cue breakup tears.

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