Grey's Anatomy: If This Video Doesn't Make You Ship MerLuca, We Don't Know What to Tell You

Sometimes you just need to put on some Ariana Grande and get to jamming — whether you're at work or not. Ellen Pompeo clearly understands this, since the 49-year-old Grey's Anatomy star posted a video to her Instagram page of her doing exactly that. Joined by her costar Giacomo Gianniotti, who plays DeLuca on the series, Pompeo channeled her inner Fly Girl and put her moves to work for Grande's new song "Break Up With Your Girlfriend, I'm Bored" while on a break from filming.

"Sometimes . . . on set antics make you channel @arianagrande you're welcome," Pompeo captioned the video, which was filmed by Sam Hellmann.

Of course, Grande — who is a well-known Grey's fan — caught wind of the video and responded with sheer incredulity. "HELP ME JESUS," the 25-year-old singer commented — which, to be fair, is the only proper response to seeing Meredith Grey getting down to your song. Grande also posted the video to her Instagram, writing, "Guys if I'm honest ......... this is the best thing that's ever happened to me. @ellenpompeo I love u sm. I cant breathe. I'll never be the same."

We can't blame Grande for being overwhelmed considering she just dropped the single on Feb. 8, as well as an entire fifth album, and won her first-ever Grammy for best pop vocal album for Sweetener on Sunday. She's obviously on an emotional roller coaster right now.

As for Pompeo and Gianniotti, their sweet on-set moment definitely ignited the MerLuca love among Grey's fans. The big question now is will they have an official couple song and will it be one from Grande's impressive collection of love songs? Make it happen, Shonda!