Hilary Duff as Lizzie McGuire
Duff will return to anchor the show as Lizzie, now a 30-year-old designer's assistant in New York. As a teenager, Duff starred in teen flicks like Agent Cody Banks, Cheaper by the Dozen, and A Cinderella Story. She also began a music career, releasing five studio albums over a handful of years.
In 2015, Duff returned to TV full-time, playing ambitious editor Kelsey Peters on the TVLand comedy Younger, starring opposite Sutton Foster as Liza. She's set to return for season seven; word is that the Lizzie McGuire reboot will not interfere with her filming schedule for Younger or vice versa.