These 25 Actors Passed on the Role of a Lifetime, but Most of Them Didn't Regret It

Way back in 2009, MTV broke the news that Emily Blunt had dropped out after being cast as Black Widow in Iron Man 2. Scarlett Johansson — reportedly after losing the role to Blunt the first time around — wound up playing the role and remained in it for a full decade of movies. Blunt's reason for dropping out was a simple one, she told MTV: scheduling conflicts with Gulliver's Travels, which she'd already committed to. "It was one of things that was conflicting," she said. "So it's a shame the two of them couldn't work together. It just got complicated, so I think I had to pull out for my own sanity more than anything."