17 Longest Running TV Shows of All Time, From "Grey's Anatomy" to "SVU"

• Seasons: 14
• Episodes: 435

Despite featuring real-life family members Ozzie and Harriet Nelson, along with their two sons, David and Ricky, the show is a scripted sitcom. It highlights family dynamics while also tackling common life topics like dating and working. The show was the longest-running live-action sitcom before technically getting outrun by "It's Always Sunny in Philadelphia" in December 2021, per NPR. However, thanks to its astronomical episode count, "The Adventures of Ozzie and Harriet" edged out "Always Sunny" on this list.