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Based on the true story of John and Aileen Crowley, "Extraordinary Measures" centers around John (Fraser) and Aileen (Keri Russell) whose two children suffer from Pompe's disease. In most cases, the disease is terminal and often results in death before children turn 10, which pushes the pair to find a cure and save their children. With the help of researcher Robert Stonehill (Harrison Ford), John launches a company with the goal of funding research and conducting trials, but money and greed from competing companies threaten everything they are working for.