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It happens — you dripped some kind of food, toothpaste, or cocktail on your jeans. Instead of washing the entire pair, denim experts suggest you spot-treat just the stained area with vinegar. "I would avoid spot-cleaners that contain chlorine bleach," Ryu says. In place of a stain pen or wipe, she recommends opting for gentle soap or vinegar, which is a great alternative to harsh detergent.