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While Lady Gaga hasn't experienced obvious symptoms of the autoimmune disease, she tested borderline positive for lupus in 2010. The pop star has made it her mission to draw attention to the condition.
"So as of right now . . . I do not have it. But I have to take good care of myself," she confirmed on an episode of "Larry King Live" in June 2010.
In 2016, she released an album inspired by her aunt Joanne, who died of lupus in 1974. Relatives of people with lupus have a greater chance of developing lupus, according to Johns Hopkins Medicine. And it's possible for the disease to lie dormant for decades and be triggered by a variety of factors, including stress, medication, or infection.