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Is There a TV Costar Curse? 32 Couples That Couldn't Make It Work
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Sophia Bush and Chad Michael Murray

Chad Michael Murray and Sophia Bush met on the set of One Tree Hill in 2003 and tied the knot in 2005 after dating for two years. Unfortunately, just like in their onscreen relationship, the couple called it quits — they annulled their marriage and separated just five months later.

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