These Actors and Actresses Have Played Both Siblings and Love Interests

McGowen and Arquette played Tatum Riley and Deputy Dewey Riley in the original 1996 Scream.

These two first starred in The Dangerous Lives of Altar Boys back in 2002. Hirsch played Francis, one of the guys in a group of friends who falls for Margie (Malone).

In 2007, Hirsch memorably played Chris McCandless in Into the Wild. But did you remember that Malone portrayed his sister, Carine?

Saturday Night Live costars Hader and Wiig teamed up for 2008's Adventureland. They play Bobby and Paulette, the husband and wife team who run a local amusement park.

They reunited in 2014 to play siblings Milo and Maggie in The Skeleton Twins.

Collette and Carell first starred as sister and brother duo Sheryl and Frank in 2006's Little Miss Sunshine.

In 2013, they returned to the big screen in The Way Way Back, a comedy about a kid who's having trouble dealing with his mom (Collette) and her boyfriend (Carell).

Phillippe and Gellar play a couple who are stalked by a serial killer in the classic 1997 hit, I Know What You Did Last Summer.

Two years later, they portrayed spoiled stepsiblings Sebastian and Kathryn in Cruel Intentions. Weirdly, they have way more sexual chemistry here.

Not only do Rudd and Banks make out in a really hardcore way in Wet Hot American Summer, they also play a couple in 2008's Role Models.

Banks later played Rudd's sister in the indie comedy Our Idiot Brother.

British pair Thompson and Grant starred in 1995's Jane Austen adaptation as Elinor Dashwood and Edward Ferrars, who — spoiler alert — get married.

Then in 2003, they played a brother-sister pair in Love Actually.

Though Olsen doesn't get much screen time, she does play Taylor-Johnson's wife in 2014's Godzilla.

A year later, the two appeared as Scarlet Witch and Quicksilver, siblings with superpowers, in Avengers: Age of Ultron.

Woodley and Elgort are famous for playing siblings Tris and Caleb Prior in the Divergent movies.

Of course, we also watched them fall in love as Hazel and Gus in John Green's The Fault in Our Stars.